Plasma membrane and cytoskeleton dynamics during single-cell wound healing

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منابع مشابه

Plasma proteins and wound healing.

In response to injury, the concentrations of several plasma proteins are characteristically altered. In part, these changes reflect an essential contribution of many of these proteins, acting in concert, to the processes involved in wound healing. There is evidence that plasma proteins support tissue repair by metabolic as well as functional activity. Specifically, plasma proteins may directly ...

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Institute of Botany, Department of Plant Cell Biology, Rheinische Friedrich-Wilhelms University of Bonn, 53115 Bonn, Germany (F.B., J.Š., P.W., D.V., D.M.); Institute of Plant Genetics and Biotechnology, Slovak Academy of Sciences, Akademicka 2, SK–949 01 Nitra, Slovak Republic (J.Š.); Institute of Molecular Biology and Biotechnology, Adam Mickiewicz University, 61–701 Poznań, Poland (P.W.); an...

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Membrane dynamics during cellular wound repair

Cells rapidly reseal after damage, but how they do so is unknown. It has been hypothesized that resealing occurs due to formation of a patch derived from rapid fusion of intracellular compartments at the wound site. However, patching has never been directly visualized. Here we study membrane dynamics in wounded Xenopus laevis oocytes at high spatiotemporal resolution. Consistent with the patch ...

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Plasma membrane calcium-ATPase isoform four distribution changes during corneal epithelial wound healing

PURPOSE Plasma Membrane Calcium-ATPases (PMCAs) are integral membrane proteins essential to the control of intracellular Ca2+ concentration. In humans, four genes encode PMCA proteins termed PMCA1-PMCA4. PMCA4 is the major PMCA isoform expressed in human corneal epithelium (hCE); however, little is known about its role. The present study documented expression of PMCA4 in rabbit CE (rbCE) and fo...

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Coordination of Membrane and Actin Cytoskeleton Dynamics during Filopodia Protrusion

Leading edge protrusion of migrating cells involves tightly coordinated changes in the plasma membrane and actin cytoskeleton. It remains unclear whether polymerizing actin filaments push and deform the membrane, or membrane deformation occurs independently and is subsequently stabilized by actin filaments. To address this question, we employed an ability of the membrane-binding I-BAR domain of...

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ژورنال

عنوان ژورنال: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

سال: 2015

ISSN: 0167-4889

DOI: 10.1016/j.bbamcr.2015.07.012